Sayed IM, Chakraborty A, . Assays with Patient-Derived Organoids to Evaluate the Impact of Microbial Infection on Base Excision Repair (BER) Enzymes. Methods Mol Biol. 2023;2701:157-172. doi: 10.1007/978-1-0716-3373-1_10. PMID: 37574481

Ghosh P, Sinha S, Katkar GD, Vo D, Taheri S, Dang D, , Sahoo D. Machine learning identifies signatures of macrophage reactivity and tolerance that predict disease outcomes. EBioMedicine. 2023 Aug: 94:104719. doi: 10.1016/j.ebiom.2023.104719. Epub 2023 Jul 27. PMID: 37516087

Jati S, Mahata S, , Chatterjee S, Mahata SK. Catestatin: Antimicrobial Functions and Potential Therapeutics. Pharmaceutics. 2023 May 20;15(5):1550. doi: 10.3390/pharmaceutics15051550. PMID: 37242791

Das S. Linking SARS-CoV-2 to the circadian clock. Nat Cell Biol. 2023 Mar;25(3):373-374. doi: 10.1038/s41556-023-01099-8. PMID: 36918694

Sharma A*, Achi SC*, Ibeawuchi SR*, Anandachar MS, Gementera H, Chaudhury U, Usmani F, Vega K, Sayed IM, Das S. The crosstalk between microbial sensors ELMO1 and NOD2 shape intestinal immune responses. (*Contributed equally). Virulence. 2023 Dec;14(1):2171690. doi: 10.1080/21505594.2023.2171690. PMID: 36694274

Sayed IM, Bhattacharyya A, Das S. Editorial: Microbial sensing to control host immune responses. Front Microbiol. 2022 Oct 11;13:1054640. doi: 10.3389/fmicb.2022.1054640. eCollection 2022. PMID: 36304953

Ghosh P, Campos VJ, Vo DT, Guccione C, Goheen-Holland V, Tindle C, Mazzini GS, He Y, Alexandrov LB, Lippman SM, Gurski RR, Das S, Yadlapati R, Curtius K, Sahoo D. AI-assisted discovery of an ethnicity-influenced driver of cell transformation in esophageal and gastroesophageal junction adenocarcinomas. JCI Insight. 2022 Sep 22;7(18):e161334. doi: 10.1172/jci.insight.161334. PMID: 36134663

Tocci S, Ibeawuchi SR, Das S, Sayed IM. Role of ELMO1 in inflammation and cancer-clinical implications. Cell Oncol (Dordr). 2022 Aug;45(4):505-525. doi: 10.1007/s13402-022-00680-x. Epub 2022 Jun 6. PMID: 35668246

Ghosh P, Katkar GD, Shimizu C, Kim J, Khandelwal S, Tremoulet AH, Kanegaye JT; Pediatric Emergency Medicine Kawasaki Disease Research Group, Bocchini J, Das S, Burns JC, Sahoo D. An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease. Nature Commun. 2022 Aug 11;13(1):4729. doi: 10.1038/s41467-022-32479-7. PMID: 35953486

Achi S, Karimilangi S, Lie D, Sayed IM, . The WxxxE proteins in microbial pathogenesis. . 2022 Mar 14:1-17. doi: 10.1080/1040841X.2022.2046546. PMID: 35287539

Quach A, Jayaratne RR, Lee BJ, Ibeawuchi SR, Lim E, Das S, Barrett KE. Diarrheal pathogenesis in Salmonella infection may result from an imbalance in intestinal epithelial differentiation through reduced Notch signaling. J Physiol. 2022 Jan 31. doi: 10.1113/JP282585. PMID: 35100665

Sayed IM, Ibeawuchi SR, Lie D, Anandachar MS, Pranadinata R, Manuela Raffatellu M, Das S. The interaction of enteric bacterial effectors with the host engulfment pathway controls innate immune responses. Gut Microbes, 2021 Jan-Dec;13(1):1991776. doi: 10.1080/19490976.2021.1991776. PMID: 34719317

Long T, Abbasi N, Hernandez JH, Li Y, Sayed IM, Ma S, Iemolo A, Yee B, Yeo G, Telese F, Ghosh P, Das S, Huang WJM. RNA binding protein DDX5 directs tuft cell specification and function to regulate microbial repertoire and disease susceptibility in the intestine. Gut, 2021 Sep;71(9):1790-1802. doi: 10.1136/gutjnl-2021-324984. PMID: 34853057

Vo DT, Fuller MR, Tindle C, Anandachar MS, Das S, Sahoo D, Ghosh P. SPT6 loss Permits the Transdifferentiation of Keratinocytes into an Intestinal Fate that Recapitulates Barrett’s Metaplasia. iScience., Sep11;24(10):103121. doi: 10.1016/j.isci.2021.103121. eCollection 2021 Oct 22. PMID: 34622168

Tindle C†, Fuller M†, Fonseca A†, Taheri A†, Katkar GD, Ibeawuchi, Beutler N, Claire A, Castillo A, Hernandez A, Russo H, Duran J, Alexander LC, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R*, Rogers TF*, Sahoo D*, Ghosh P*, *. Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19. . Aug 31st, 2021, 10:e66417. doi: 10.7554/eLife.66417. (†Equally Contributed, *Corresponding authors).

Sahoo D*†, Swanson L†, Sayed IM †$,  Katkar GD, Ibeawuchi SR, Lim BB, Mittal Y, Pranadinata RF, Tindle C, Fuller M, Stec DL, Chang JT, Sandborn WJ, Das S* and Ghosh P*, AI-guided Discovery of a Barrier-Protective Therapy in Inflammatory Bowel Disease. (†Equally Contributed, *Corresponding authors)-Nature Communications. 2021 Jul 12;12(1):4246. doi: 10.1038/s41467-021-24470-5. PMID: 34253728. (This work is also highlighted in the newspaper and to GEN-https://lnkd.in/gt9uQAu).

Sayed IM, Tindle C, Fonseca AG, Ghosh P, Das S. Functional assays with human patient-derived enteroid monolayers to assess the human gut barrier. STAR Protocol. 2021 Jul 17;2(3):100680. doi: 10.1016/j.xpro.2021.100680. eCollection 2021 Sep 17. PMID: 34337445

Sayed IM, El-Hafeez AAA, Maity PP, Das S, Ghosh P. Modeling colorectal cancers using multidimensional organoids. Adv Cancer Res. 2021;151:345-383. doi: 10.1016/bs.acr.2021.02.005. Epub 2021 Mar 26. PMID: 34148617

Sahoo D*; Katkar GD; Khandelwal S; Behroozikhah M; Claire A; Castillo V; Tindle C; Fuller M; Taheri S; Rogers T.F.; Beutler N; Ramirez S.I.; Rawlings. S.A; Pretorius V; Smith D.M; Burton D.R; Alexander L.E.C; Duran J; Crotty S; Dan J.M; Das S*; Ghosh P*. AI-guided discovery of the invariant host response to viral pandemics. EBioMedicine, (*Co-Corresponding). 2021;68:103390. doi: 10.1016/j.ebiom.2021.103390. Epub 2021 Jun 11. PMID: 34127431

Bakowski M, Beutler N, Wolff K, Kirkpatrick M, Chen E, Nguyen T-T, Riva L, Shaabani N, Parren M, Ricketts J, Gupta A, Pan K, Kuo P, Fuller M, Garcia E, Teijaro J, Yang L, Sahoo D, Chi V, Huang E, Vargas N, Roberts A, Das S, Ghosh P, Woods A, Joseph S, Schultz P, Burton D, Chatterjee A, McNamara C, Rogers T, and Hull M. Drug repurposing screens identify chemical entities for the development of COVID-19 interventions. Nature Communications, Jun 3;12(1):3309. doi: 10.1038/s41467-021-23328-0. PMID: 34083527

Sharma A, Lee J, Fonseca AG, Moshensky A, Kothari T, Sayed IM, Ibeawuchi SR, Pranadinata RF., Ear J, Sahoo D, Crotty-Alexander L*, Ghosh P* and Das S* E-cigarettes compromise the gut barrier, trigger inflammation. (*Equally Contributed), iScience 2021. Jan 6; 24(2):102035. PMID: 33537654

Swanson L, Katkar G.D., Tam J, Pranadinata R.F., Chareddy Y, Coates J, Castillo V, Olson J, Nizet V, Kufareva I, Das S, Ghosh P. TLR4 signaling, and macrophage inflammatory responses are dampened by GIV/Girdin. PNAS. 2020 Oct 27;117(43):26895-26906. doi: 10.1073/pnas.2011667117. PMID: 33055214

Abbasi N, Long T, Li Y, Yee B, Cho B, Hernandez J, Ma E, Patel P, Sahoo D, Sayed I, Varki N, Das S, Ghosh P, Yeo G, and Huang W. DDX5 promotes oncogene C3 and FABP1 expressions and drives intestinal inflammation and tumorigenesis. Life Science Alliance. 2020. Aug 18;3(10):e202000772. doi: 10.26508/lsa.202000772. PMID: 32817263

Sayed IM, Chakraborty A, Ali A, Sahan AZ, Huang W, Sahoo D, Ghosh P, Hazra TK, Das S. DNA glycosylase NEIL2 prevents Fusobacterium-mediated inflammation and DNA damage in colonic epithelial cells. Cells, MDPI, special issue Special Issue "Double-Strand DNA Break Repair and Human Disease". 2020 Aug 28;9(9): E1980. doi: 10.3390/cells9091980. PMID: 32872214

Kim Y, Quach A, Das S, Barrett KE. Potentiation of calcium-activated chloride secretion and barrier dysfunction may underlie EGF receptor tyrosine kinase inhibitor-induced diarrhea. Physiol Rep. 2020 Jul;8(13):e14490. doi: 10.14814/phy2.14490

Sayed IM$, Sahan AZ$, Venkova T, Chakraborty A, Mukhopadhyay D, Bimczok D, Beswick EJ, Reyes VE, Pinchuk I, Sahoo D, Ghosh P, Hazra TK*, *. infection down-regulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells. J Biol Chem. 2020 Jun 9:jbc.RA119.009981. doi: 10.1074/jbc.RA119.009981. PMID: 32518160. ($Equally Contributed, *Equally Contributed, Co-Corresponding).

Sayed IM*, Suarez K*, Lim E*, Singh S*, Pereira M, Ibeawuchi SR, Katkar G, Dunkel Y, Mittal Y, Chattopadhyay R, Guma M, Boland BS, Dulai PS, Sandborn WJ, Ghosh P, and . Host engulfment pathway controls inflammation in Inflammatory Bowel Disease. The FEBS Journal. 2020 Jan 30. doi: 10.1111/febs.15236. PMID: 32003126 (*equally contributed)

Ghosh P*, Swanson L, Sayed IM, Mittal Y, Lim BB, Ibeawuchi SR, Foretz M, Viollet B, Sahoo D and *. The Stress Polarity Signaling (SPS)-Pathway Serves as a Marker and a Target in the Leaky Gut barrier: Implications in Aging and Cancer.. Feb 10, 2020 0;3(3). pii: e201900481. PMID: 32041849 (* equally contributed, Co-Corresponding).

Sahan A, Venkova T.B., Hazra TK, Das S. The pivotal role of DNA repair in infection mediated inflammation and cancer. Frontiers in Microbiology, in its “Evolutionary and Genomic Microbiology” section 2018, Apr 11; 9:663. doi: 10.3389/fmicb.2018.00663. PMID: 29696001

Das S, Jayaratne R, Barrett K.E. The role of ion transporters in the pathophysiology of infectious diarrhea. 2018, Review in Cellular and Molecular Gastroenterology and Hepatology. 2018; 6:33–45. doi: 10.1016/j.jcmgh.2018.02.009. PMID: 29928670

Sarkar A$, Tindle C$, Pranadinata RF$, Reed S, Eckmann L, Stappenbeck TS, Ernst PB*, Das S*. ELMO1 Regulates Autophagy Induction and Bacterial Clearance During Enteric Infection. J Infect Dis. 2017 Dec19;216(12):1655-1666. PMID: 29029244. $* Contributed equally.